Gamage, Swarna: search on Z-Library

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1

Recent developments in anticancer drug delivery using cell penetrating and tumor targeting peptides

Dissanayake, Shama, Denny, William A, Gamage, Swarna, Sarojini, Vijayalekshmi

Journal:

Journal of Controlled Release

Year:

2017

Language:

english

File:

PDF, 1.06 MB

english, 2017

2

Synthesis and biological evaluation of novel phosphatidylinositol 3-kinase inhibitors: Solubilized 4-substituted benzimidazole analogs of 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole (ZSTK474)

Rewcastle, Gordon W., Gamage, Swarna A., Flanagan, Jack U., Kendall, Jackie D., Denny, William A., Baguley, Bruce C., Buchanan, Christina M., Chao, Mindy, Kestell, Philip, Kolekar, Sharada, Lee, Woo-J

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.06 MB

english, 2013

3

Synthesis and Biological Evaluation of Novel Analogues of the Pan Class I Phosphatidylinositol 3-Kinase (PI3K) Inhibitor 2-(Difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole (ZSTK474)

Rewcastle, Gordon W., Gamage, Swarna A., Flanagan, Jack U., Frederick, Raphael, Denny, William A., Baguley, Bruce C., Kestell, Philip, Singh, Ripudaman, Kendall, Jackie D., Marshall, Elaine S.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.06 MB

english, 2011

4

Activation of 3-Amino-1,2,4-benzotriazine 1,4-Dioxide Antitumor Agents to Oxidizing Species Following Their One-Electron Reduction

Anderson, Robert F., Shinde, Sujata S., Hay, Michael P., Gamage, Swarna A., Denny, William A.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 263 KB

english, 2003

5

Structure−Activity Relationships for Substituted Bis(acridine-4-carboxamides): A New Class of Anticancer Agents

Gamage, Swarna A., Spicer, Julie A., Atwell, Graham J., Finlay, Graeme J., Baguley, Bruce C., Denny, William A.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 205 KB

english, 1999

6

Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis

Evans, Genevieve L., Gamage, Swarna A., Bulloch, Esther M. M., Baker, Edward N., Denny, William A., Lott, J. Shaun

Journal:

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

7

Corrigendum: Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis

Evans, Genevieve L., Gamage, Swarna A., Bulloch, Esther M. M., Baker, Edward N., Denny, William A., Lott, J. Shaun

Journal:

Year:

2015

Language:

english

File:

PDF, 267 KB

english, 2015

8

Structure–activity relationships for 4-anilinoquinoline derivatives as inhibitors of the DNA methyltransferase enzyme DNMT1

Gamage, Swarna A., Brooke, Darby G., Redkar, Sanjeev, Datta, Jharna, Jacob, Samson T., Denny, William A.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 631 KB

english, 2013

9

Phenazine-1-carboxamides: Structure–cytotoxicity relationships for 9-substituents and changes in the H-bonding pattern of the cationic side chain

Swarna A. Gamage, Gordon W. Rewcastle, Bruce C. Baguley, Peter A. Charlton, William A. Denny

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 198 KB

english, 2006

10

Structure−Activity Relationships of 1,2,4-Benzotriazine 1,4-Dioxides as Hypoxia-Selective Analogues of Tirapazamine

Hay, Michael P., Gamage, Swarna A., Kovacs, Mary S., Pruijn, Frederik B., Anderson, Robert F., Patterson, Adam V., Wilson, William R., Brown, J. Martin, Denny, William A.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 195 KB

english, 2003

11

DNA-Targeted 1,2,4-Benzotriazine 1,4-Dioxides: Potent Analogues of the Hypoxia-Selective Cytotoxin Tirapazamine

Hay, Michael P., Pruijn, Frederik B., Gamage, Swarna A., Liyanage, H. D. Sarath, Kovacs, Mary S., Patterson, Adam V., Wilson, William R., Brown, J. Martin, Denny, William A.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 206 KB

english, 2004

12

Structure−Activity Relationships for the Antileishmanial and Antitrypanosomal Activities of 1‘-Substituted 9-Anilinoacridines

Gamage, Swarna A., Figgitt, David P., Wojcik, Stanley J., Ralph, Raymond K., Ransijn, Adriana, Mauel, Jacques, Yardley, Vanessa, Snowdon, Diane, Croft, Simon L., Denny, William A.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 280 KB

english, 1997

13

Radical properties governing the hypoxia-selective cytotoxicity of antitumor 3-amino-1,2,4-benzotriazine 1,4-dioxides

Anderson, Robert F., Shinde, Sujata S., Hay, Michael P., Gamage, Swarna A., Denny, William A.

Journal:

Organic & Biomolecular Chemistry

Year:

2005

Language:

english

File:

PDF, 227 KB

english, 2005

14

Structure–activity relationships for ketamine esters as short-acting anaesthetics

Jose, Jiney, Gamage, Swarna A., Harvey, Martyn G., Voss, Logan J., Sleigh, James W., Denny, William A.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 684 KB

english, 2013

15

Structure−Activity Relationships for Acridine-Substituted Analogues of the Mixed Topoisomerase I/II Inhibitor N -[2-(Dimethylamino)ethyl]acridine-4-carboxamide

Spicer, Julie A., Gamage, Swarna A., Atwell, Graham J., Finlay, Graeme J., Baguley, Bruce C., Denny, William A.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 267 KB

english, 1997

16

Development of Rapidly Metabolized and Ultra-Short–Acting Ketamine Analogs

Harvey, Martyn, Sleigh, Jamie, Voss, Logan, Jose, Jiney, Gamage, Swarna, Pruijn, Frederik, Liyanage, Sarath, Denny, William

Journal:

Survey of Anesthesiology

Year:

2016

Language:

english

File:

PDF, 47 KB

english, 2016

17

Synthesis and biological evaluation of solubilized sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474

Giddens, Anna C., Gamage, Swarna A., Kendall, Jackie D., Lee, Woo-Jeong, Baguley, Bruce C., Buchanan, Christina M., Jamieson, Stephen M.F., Dickson, James M.J., Shepherd, Peter R., Denny, William A.,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2019

File:

PDF, 1.15 MB

2019

18

Dicationic Bis(9-methylphenazine-1-carboxamides): Relationships between Biological Activity and Linker Chain Structure for a Series of Potent Topoisomerase Targeted Anticancer Drugs

Gamage, Swarna A., Spicer, Julie A., Finlay, Graeme J., Stewart, Alistair J., Charlton, Peter, Baguley, Bruce C., Denny, William A.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 135 KB

english, 2001

19

Development of Rapidly Metabolized and Ultra-Short-Acting Ketamine Analogs

Harvey, Martyn, Sleigh, Jamie, Voss, Logan, Jose, Jiney, Gamage, Swarna, Pruijn, Frederik, Liyanage, Sarath, Denny, William

Journal:

Anesthesia & Analgesia

Year:

2015

Language:

english

File:

PDF, 770 KB

english, 2015

20

Oxidation of 2-Deoxyribose by Benzotriazinyl Radicals of Antitumor 3-Amino-1,2,4-benzotriazine 1,4-Dioxides

Shinde, Sujata S., Anderson, Robert F., Hay, Michael P., Gamage, Swarna A., Denny, William A.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 194 KB

english, 2004

21

Crystal Structure of the Pyocyanin Biosynthetic Protein PhzS †‡

Greenhagen, Bryan T., Shi, Katherine, Robinson, Howard, Gamage, Swarna, Bera, Asim K., Ladner, Jane E., Parsons, James F.

Journal:

Year:

2008

Language:

english

File:

PDF, 369 KB

english, 2008

22

Bis(phenazine-1-carboxamides): Structure−Activity Relationships for a New Class of Dual Topoisomerase I/II-Directed Anticancer Drugs

Spicer, Julie A., Gamage, Swarna A., Rewcastle, Gordon W., Finlay, Graeme J., Bridewell, David J. A., Baguley, Bruce C., Denny, William A.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 124 KB

english, 2000

23

Synthesis and in vitro Evaluation of 9-Anilino-3,6-diaminoacridines Active Against a Multidrug-Resistant Strain of the Malaria Parasite Plasmodium falciparum

Gamage, Swarna A., Tepsiri, Nisana, Wilairat, Prapon, Wojcik, Stanley J., Figgitt, David P., Ralph, Raymond K., Denny, William A.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.23 MB

english, 1994

24

Aromatic annulation with naphtho[1,8-de]-1,3-dithiin carbocations

Swarna A. Gamage, Robin A.J. Smith

Journal:

Year:

1990

Language:

english

File:

PDF, 1.32 MB

english, 1990

25

A new synthesis of substituted acridine-4-carboxylic acids and the anticancer drug N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA)

Swarna A. Gamage, Julie A. Spicer, Gordon W. Rewcastle, William A. Denny

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 201 KB

english, 1997

26

Synthesis and evaluation of unsymmetrical bis(arylcarboxamides) designed as topoisomerase-Targeted anticancer drugs

Julie A Spicer, Swarna A Gamage, Graeme J Finlay, William A Denny

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 227 KB

english, 2002

27

Structure−Activity Relationships for Pyrido-, Imidazo-, Pyrazolo-, Pyrazino-, and Pyrrolophenazinecarboxamides as Topoisomerase-Targeted Anticancer Agents

Gamage, Swarna A., Spicer, Julie A., Rewcastle, Gordon W., Milton, John, Sohal, Sukhjit, Dangerfield, Wendy, Mistry, Prakash, Vicker, Nigel, Charlton, Peter A., Denny, William A.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 77 KB

english, 2002

28

Synthesis and biological evaluation of sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474

Gamage, Swarna A., Giddens, Anna C., Tsang, Kit Y., Flanagan, Jack U., Kendall, Jackie D., Lee, Woo-Jeong, Baguley, Bruce C., Buchanan, Christina M., Jamieson, Stephen M.F., Shepherd, Peter R., Denny,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.02 MB

english, 2017

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